Alprostadil

AlprostadilAlprostadil meets USP testing specifications Molecular Weight 354.48 Beilstein Registry Number 5294062 References Prostaglandin e1 in heart disease: review and perspective. Rabinowitz B, Schollmayer E, and Weiss M Am. J. Ther. 4(11-12) . 353-8, (1997) Anticancer activity of fish oils against human lung cancer is associated with changes in formation of PGE2 and PGE3 and alteration of Akt phosphorylation. Yang P, Cartwright C, Chan D, et al. Mol. Carcinog. 53(7) . 566-77, (2014) Spectrophotometric determination of gs with iodine. Kna T, et al. J. Sci. Ind. Res. 65(10) . 808, (2006) Quantitative scture-activity relationship andplexwork approach to monoamine oxidase A and B inhibitors. Lourdes Santana et al J. Med. Chem.

51 . 6740-51, (2008)About DailyMed DailyMed provides stworthy information about marketed gs in the United States. DailyMed is the official provider of FDA label information (package inserts). This Web site provides a standard, prehensive, up-to-date, look-up and download resource of medication content and labeling found in medication package inserts. The National Library of Medicine (NLM) provides this as a public service and does not accept advertisements. The g labeling information on this Web site is the most recent submitted to the Food and g Administration (FDA) and currently in use it may include, for example, strengthened warnings undergoing FDA review or minor editorial changes. These labels have been reformatted to make them easier to read.

alprostadil Urology A formulation of PGE-1 which relaxes the corpus cavernosum, allowing ening during erection. See Erectile dysfunction. asm. Alprostadil A smooth muscle relaxant sometimes injected into the penis or applied to the urethral opening to treat impotence. al183pros183ta183dil ( al-prost259-dil ) A vasodilator used for palliative therapy to maintain patency of the ductus arteriosus in neonates with congenital heart defects temporarily.

alprostadil (alprosxB4tx259dilxB4) , n brand name: Caverject action: induces erection by relaxation of trabecular smooth muscle and by dilation of cavernosal arteries uses: treatment of erectile dysfunction caused by neurogenic, vasculogenic, psychogic, or mixed etiology. What works What works Research summarized Evidence reviews In adults, direct lung damage or indirect damage caused by trauma, infection or other factors can result in acute lung injury, including acute respiratory distress syndrome. Patients with this syndrome require mechanical ventilation. About half of patients die, and survivors have a prolonged stay in intensive care and physical limitations afterwards.

Many gs have been studied to improve lung function and reduce inflammation in these patients. The evidence to date does not convincingly show that any g saves lives, although some small studies have shown potential benefit. Idiopathic sudden sensorineural hearing loss (ISSHL) is sudden hearing loss where clinical assessment fails to reveal a cause. Hearing loss may vary from partial to total loss, and is usually apanied by tinnitus.

It has been frequently considered that ISSHL may have a vascular origin (i. e. is related to the blood circulatory system) and vasodilators and rheological substances are widely used as treatments. Vasodilators are gs which widen blood vessels and thus improve blood flow. Vasoactive/rheological substances increase flow through blood vessels in other ways (such as by altering the viscosity of fluid). We found three trials, involving 189 participants, which showed improvement in hearing thresholds in those treated with vasodilatorspared to control groups. However, as the number of patients included in the studies was small, and there were differences in the type, dosage and duration of vasodilator treatment used in each of these studies, the results could not bebined to reach a conclusion.

The effectiveness of vasodilators in the treatment of ISSHL could not be proven. Further research is needed. Preparing the cervix to make it softer and more open before a woman has an abortion may make the procedure easier and safer. There are different techniques for preparing the cervix before abortion, including several types of medications taken either by mouth, injection or placed in the vagina, as well as several types of small rods that can be placed within the cervix. This review found that cervical preparation decreased the length of time necessary for an abortion procedure, but did not seem to decrease rates of umon abortionplications. The medication called misoprostol worked better with less sideeffects than other similar medications. Misoprostol is most effective with the least sideeffects when placed in the vagina, but when placed under the tongue it is equally effective. Another g called mifepristone worked better than misoprostol however, it is more expensive to use. All methods of preparation take at least 23 hours or more to work. The review could not determine whether women preferred one method best.

Summaries for consumers In adults, direct lung damage or indirect damage caused by trauma, infection or other factors can result in acute lung injury, including acute respiratory distress syndrome. Patients with this syndrome require mechanical ventilation. About half of patients die, and survivors have a prolonged stay in intensive care and physical limitations afterwards. Many gs have been studied to improve lung function and reduce inflammation in these patients. The evidence to date does not convincingly show that any g saves lives, although some small studies have shown potential benefit. Preparing the cervix to make it softer and more open before a woman has an abortion may make the procedure easier and safer.

There are different techniques for preparing the cervix before abortion, including several types of medications taken either by mouth, injection or placed in the vagina, as well as several types of small rods that can be placed within the cervix. This review found that cervical preparation decreased the length of time necessary for an abortion procedure, but did not seem to decrease rates of umon abortionplications. The medication called misoprostol worked better with less sideeffects than other similar medications. Misoprostol is most effective with the least sideeffects when placed in the vagina, but when placed under the tongue it is equally effective. Another g called mifepristone worked better than misoprostol however, it is more expensive to use. All methods of preparation take at least 23 hours or more to work. The review could not determine whether women preferred one method best.

Hearing Aids

Hearing AidsHearing Aids On this page: What is a hearing aid A hearing aid is a small electronic device that you wear in or behind your ear. It makes some sounds louder so that a person with hearing loss can listen, municate, and participate more fully in daily activities. A hearing aid can help people hear more in both quiet and noisy situations. However, only about one out of five people who would benefit from a hearing aid actually uses one. A hearing aid has three basic parts: a microphone, amplifier, and speaker. The hearing aid receives sound through a microphone, which converts the sound waves to electrical signals and sends them to an amplifier. The amplifier increases the power of the signals and then sends them to the ear through a speaker. How can hearing aids help Hearing aids are primarily useful in improving the hearing and speechprehension of people who have hearing loss that results from damage to the small sensory cells in the inner ear, called hair cells. This type of hearing loss is called sensorineural hearing loss.

The damage can occur as a result of disease, aging, or injury from noise or certain medicines. A hearing aid magnifies sound vibrations entering the ear. Surviving hair cells detect the larger vibrations and convert them into neural signals that are passed along to the brain. The greater the damage to a persons hair cells, the more severe the hearing loss, and the greater the hearing aid amplification needed to make up the difference. However, there are practical limits to the amount of amplification a hearing aid can provide. In addition, if the inner ear is too damaged, even large vibrations will not be converted into neural signals.

In this situation, a hearing aid would be ineffective. How can I find out if I need a hearing aid If you think you might have hearing loss and could benefit from a hearing aid, visit your physician, who may refer you to an otolaryngologist or audiologist. An otolaryngologist is a physician who specializes in ear, nose, and throat disorders and will investigate the cause of the hearing loss. An audiologist is a hearing health professional who identifies and measures hearing loss and will perform a hearing test to assess the type and degree of loss. Are there different styles of hearing aids Styles of hearing aids Credit: NIH Medical Arts Behind-the-ear (BTE) hearing aids consist of a hard plastic case worn behind the ear and connected to a plastic earmold that fits inside the outer ear. The electronic parts are held in the case behind the ear. Sound travels from the hearing aid through the earmold and into the ear. BTE aids are used by people of all ages for mild to profound hearing loss. A new kind of BTE aid is an open-fit hearing aid. Small, open-fit aids fit behind the earpletely, with only a narrow tube inserted into the ear canal, enabling the canal to remain open. For this reason, open-fit hearing aids may be a good choice for people who experience a buildup of earwax, since this type of aid is less likely to be damaged by such substances. In addition, some people may prefer the open-fit hearing aid because their perception of their voice does not sound plugged up. In-the-ear (ITE) hearing aids fitpletely inside the outer ear and are used for mild to severe hearing loss. The case holding the electronicponents is made of hard plastic.

Some ITE aids may have certain added features installed, such as a telecoil. A telecoil is a small maic coil that allows users to receive sound through the circuitry of the hearing aid, rather than through its microphone. This makes it easier to hear conversations over the telephone. A telecoil also helps people hear in public facilities that have installed special sound systems, called induction loop systems.

Induction loop systems can be found in many churches, schools, airports, and auditoriums. ITE aids usually are not worn by young children because the casings need to be replaced often as the ear grows. Canal aids fit into the ear canal and are available in two styles. The in-the-canal (ITC) hearing aid is made to fit the size and shape of a persons ear canal.

Apletely-in-canal (CIC) hearing aid is nearly hidden in the ear canal. Both types are used for mild to moderately severe hearing loss. Because they are small, canal aids may be difficult for a person to adjust and remove. In addition, canal aids have less space available for batteries and additional devices, such as a telecoil. They usually are not rmended for young children or for people with severe to profound hearing loss because their reduced size limits their power and volume. Do all hearing aids work the same way Hearing aids work differently depending on the electronics used. The two main types of electronics are analog and digital. Analog aids convert sound waves into electrical signals, which are amplified. Analog/adjustable hearing aids are custom built to meet the needs of each user.

The aid is programmed by the manufacturer according to the specifications rmended by your audiologist. Analog/programmable hearing aids have more than one program or setting. An audiologist can program the aid using aputer, and you can change the program for different listening environmentsfrom a small, quiet room to a crowded restaurant to large, open areas, such as a theater or stadium. Analog/programmable circuitry can be used in all types of hearing aids.

Analog aids usually are less expensive than digital aids. Digital aids convert sound waves into numerical codes, similar to the binary code of aputer, before amplifying them. Because the code also includes information about a sounds pitch or loudness, the aid can be specially programmed to amplify some frequencies more than others. Digital circuitry gives an audiologist more flexibility in adjusting the aid to a users needs and to certain listening environments.

These aids also can be programmed to focus on soundsing from a specific direction. Digital circuitry can be used in all types of hearing aids. Which hearing aid will work best for me The hearing aid that will work best for you depends on the kind and severity of your hearing loss. If you have a hearing loss in both of your ears, two hearing aids are generally rmended because two aids provide a more natural signal to the brain.

Hearing in both ears also will help you understand speech and locate where the sound ising from. You and your audiologist should select a hearing aid that best suits your needs and lifestyle. Price is also a key consideration because hearing aids range from hundreds to several thousand dollars. Similar to other equipment purchases, style and features affect cost. However, dont use price alone to determine the best hearing aid for you. Just because one hearing aid is more expensive than another does not necessarily mean that it will better suit your needs. A hearing aid will not restore your normal hearing. With practice, however, a hearing aid will increase your awareness of sounds and their sources. You will want to wear your hearing aid regularly, so select one that is convenient and easy for you to use. Other features to consider include parts or services covered by the warranty, estimated schedule and costs for maintenance and repair, options and upgrade opportunities, and the hearing aidpanys reputation for quality and customer service.

What questions should I ask before buying a hearing aid Before you buy a hearing aid, ask your audiologist these important questions: What features would be most useful to me What is the total cost of the hearing aid Do the benefits of newer technologies outweigh the higher costs Is there a trial period to test the hearing aids (Most manufacturers allow a 30- to 60-day trial period during which aids can be returned for a refund.) What fees are nonrefundable if the aids are returned after the trial period How long is the warranty Can it be extended Does the warranty cover future maintenance and repairs Can the audiologist make adjustments and provide servicing and minor repairs Will loaner aids be provided when repairs are needed What insction does the audiologist provide How can I adjust to my hearing aid Hearing aids take time and patience to use successfully. Wearing your aids regularly will help you adjust to them. Be familiar with your hearing aids features. With your audiologist present, practice putting in and taking out the aid, cleaning it, identifying right and left aids, and replacing the batteries. Ask how to test it in listening environments where you have problems with hearing. Learn to adjust the aids volume and to program it for sounds that are too loud or too soft. Work with your audiologist until you arefortable and satisfied.

You may experience some of the following problems as you adjust to wearing your new aid. My hearing aid feels ufortable. Some individuals may find a hearing aid to be slightly ufortable at first. Ask your audiologist how long you should wear your hearing aid while you are adjusting to it. My voice sounds too loud. The plugged-up sensation that causes a hearing aid users voice to sound louder inside the head is called the occlusion effect, and it is verymon for new hearing aid users. Check with your audiologist to see if a correction is possible. Most individuals get used to this effect over time. I get feedback from my hearing aid. A whistling sound can be caused by a hearing aid that does not fit or work well or is clogged by earwax or fluid.

See your audiologist for adjustments. I hear background noise. A hearing aid does notpletely separate the sounds you want to hear from the ones you do not want to hear. Sometimes, however, the hearing aid may need to be adjusted. Talk with your audiologist. I hear a buzzing sound when I use my cell phone. Some people who wear hearing aids or have implanted hearing devices experience problems with the radio frequency interference caused by digital cell phones. Both hearing aids and cell phones are improving, however, so these problems are occurring less often. When you are being fitted for a new hearing aid, take your cell phone with you to see if it will work well with the aid. How can I care for my hearing aid Proper maintenance and care will extend the life of your hearing aid. Make it a habit to: Keep hearing aids away from heat and moisture.

Clean hearing aids as inscted. Earwax and ear drainage can damage a hearing aid. Avoid using hairspray or other hair care products while wearing hearing aids. Turn off hearing aids when they are not in use. Replace dead batteries immediately. Keep replacement batteries and small aids away from children and pets. Are new types of aids available Although they work differently than the hearing aids described above, implantable hearing aids are designed to help increase the transmission of sound vibrations entering the inner ear. A middle ear implant (MEI) is a small device attached to one of the bones of the middle ear. Rather than amplifying the sound traveling to the earm, an MEI moves these bones directly. Both techniques have the result of strengthening sound vibrations entering the inner ear so that they can be detected by individuals with sensorineural hearing loss. A bone-anchored hearing aid (BAHA) is a small device that attaches to the bone behind the ear. The device transmits sound vibrations directly to the inner ear through the skull, bypassing the middle ear. BAHAs are generally used by individuals with middle ear problems or deafness in one ear. Because surgery is required to implant either of these devices, many hearing specialists feel that the benefits may not outweigh the risks. Can I obtain financial assistance for a hearing aid Hearing aids are generally not covered by health insurancepanies, although some do. For eligible children and young adults ages 21 and under, Medicaid will pay for the diagnosis and treatment of hearing loss, including hearing aids, under the Early and Periodic Screening, Diagnostic, and Treatment (EPSDT) service. Also, children may be covered by their states early intervention program or State Childrens Health Insurance Program.

Medicare does not cover hearing aids for adults however, diagnostic evaluations are covered if they are ordered by a physician for the purpose of assisting the physician in developing a treatment plan. Since Medicare has declared the BAHA a prosthetic device and not a hearing aid, Medicare will cover the BAHA if other coverage policies are met. Some nonprofitanizations provide financial assistance for hearing aids, while others may help provide used or refurbished aids. Contact the National Institute on Deafness and Othermunication Disorders (NIDCD) Information Clearinghouse with questions aboutanizations that offer financial assistance for hearing aids. What research is being done on hearing aids Researchers are looking at ways to apply new signal processing strategies to the design of hearing aids. Signal processing is the method used to modify normal sound waves into amplified sound that is the best possible match to the remaining hearing for a hearing aid user. NIDCD-funded researchers also are studying how hearing aids can enhance speech signals to improve understanding. In addition, researchers are investigating the use ofputer-aided technology to design and manufacture better hearing aids.

Researchers also are seeking ways to improve sound transmission and to reduce noise interference, feedback, and the occlusion effect. Additional studies focus on the best ways to select and fit hearing aids in children and other groups whose hearing ability is hard to test. Another promising research focus is to use lessons learned from animal models to design better microphones for hearing aids. NIDCD-supported scientists are studying the tiny fly Ormia ochracea because its ear scture allows the fly to determine the source of a sound easily.

Scientists are using the flys ear scture as a model for designing miniature directional microphones for hearing aids. These microphones amplify the sounding from a particular direction (usually the direction a person is facing), but not the sounds that arrive from other directions. Directional microphones hold great promise for making it easier for people to hear a single conversation, even when surrounded by other noises and voices. Where can I find additional information about hearing aids The NIDCD maintains a directory ofanizations that provide information on the normal and disordered processes of hearing, balance, taste, smell, voice, speech, and language. Use the following keywords to help you findanizations that can answer questions and provide information on hearing aids: For more information, additional addresses and phone numbers, or a printed list ofanizations, contact us at: NIDCD Information Clearinghouse 1munication Avenue Bethesda, MD 20892-3456 Toll-free Voice: (800) 241-1044 Toll-free TTY: (800) 241-1055

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Post Hair Loss Questions And Get AnswersIs Generic Finasteride as Effective as Propecia for Hair Loss I just checked Costco prices and generic Propecia (1mg finasteride) is about half the cost of name brand, but still expensive. 100 days of generic is 134. An equivalent 100 days of cut up Proscar brand (5mg finasteride) is 112, which is what I8217m taking now. If brand name Propecia is not an option for me, due to price, would it be better to get brand name Proscar or get generic Propecia (or just get generic Proscar) I hear mixed reviews on each. I of course like the price of generic Proscar the best, but want to make sure I8217m getting something effective. I have heard Proscar brand is more likely to work than generic but also heard that cutting up pills can oxidize the pills quickly and also that potentially all of the active ingredient could be in just one section of the pill so the other 3 days you may be only getting a placebo. Lots of confusing info found.

My opinion is that as long as you purchase your gs from a reputable source, generic finasteride is just as effective as name brand. I was using generic Proscar before I quit and it certainly affected my system in ways that would lead me to believe that it was doing exactly what it was supposed to do. While it8217s e that the active ingredient is not evenly distributed within the pill, the small difference in dose is not likely to be of concern when taken daily. Studies have shown that a 0.2mg dose may be nearly as effective for hair loss . I too have heard about the risk of oxidation once the protective shell of the tablet is breached. For that reason I rmend cutting only one pill a time rather than the entire supply at once.

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One pharmacy quoted 80.95 for 30 generic tabletspared to 93.85 for name brand Propecia. Not the precipitous drop in price that many were hoping for. To learn more about Propecia, its benefits and potential side effects, view the following articles from our Hair Loss QampA Blog: David (TakingThePlunge) Editorial Assistant and Fm Co-Moderator for the Hair Transplantwork, the Coalition Hair Loss Learning Center, and the Hair Loss Q amp A Blog . To share ideas with other hair loss sufferers visit the hair loss fm and socialmunity Get Proven Treatments at the Best Prices by visiting our new online hair loss treatment shop.

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Miller Firm Filagra LawsuitLatest Actos Lawsuit News April 2015 8211 Actos g Maker Offers 2.2 Billion To Settle Cases According to Bloomberg Business, Takeda Pharmaceuticals is attempting to resolve its Actos and cancer risks claims by agreeing to pay over 2.2 billion. If the attorneys representing the plaintiffs agree, this would be one of the largest g settlements in the U. S. and could result in about 275,000 for each bladder cancer claim. Some attorneys may feel that this amount is not enough due to the serious injuries their clients endured after taking this diabetes g. April 2014 8211 Attorneys for Takeda Pharmaceuticals, manufacturer of Actos filed for a mis-trial in an Actos trial being heard in Las Vegas according to the Las Vegas Review-Journal. This after expert witness, Robert Cunitz, a human factors psychologist from Maryland, testified that Takeda had been aware of the potential link of Actos and bladder cancer but had downplayed the risk in the g8217s package inserts. The legal team for the g manufacturer asked for the mis-trial based on an article published in the Review-Journal concerning a political consultant David Thomas who had been the 2012 campaign manager for Judge Earley, who is the presiding judge in this case. Mr. Thomas currently works with attorney Robert Eglet who represents one of the plaintiffs in the Actos diabetes g case.

Both plaintiffs are alleging that they would not have used Actos if they have been properly warned and that by using this g, they have developed bladder cancer and have undergone multiple surgeries as a result. Judge Earley is considering sanctions for misconduct against the Actos attorneys ( Las Vegas Review-Journal 4/27/14). She has heard arguments that the g manufacturer8217s legal team have violated court orders as well as having been disrespectful to the judge by filing to have her removed from the case. Judge Earley has called their actions 8220very egregious8221 and 8220disrespectful8221 which required her to insct the jury in the Actos trial to disregard thements and gestures of one of the Takeda8217s lawyers. Plaintiffs in this case are alleging that those representing Takeda are purposely attempting to cause a mistrial. April 2014 8211 The jury in the Louisiana federal trial has awarded 1.5 million inpensatory damages and 6 billion in punitive damages.

Feary 2, 2014 - Federal Judge Rebecca Doherty, who is overseeing thousands of Actos lawsuits hasled that jurors hearing the first Actos bladder cancer bellwether trial will be told that Takeda Pharmaceuticals intentionally destroyed documentspiled by 46 current and former employees that related to the development, marketing and sale of Actos. According to an Order issued on January 27th, U. S. District Judge Rebecca Doherty of the Western District of Louisiana decided to allow the disclosure after Takeda admitted it had lost the files, some of which were deleted frompanyputers after employees were warned by executives to retain information relating to Actos. (In re: Actos Product Liability Litigation, MDL No. 2299) The breadth of Takeda leadership whose files have been lost, deleted or destroyed is, in and of itself, disturbing, Judge Doherty wrote in her Order. DePuy Hip Replacement Lawyer If you have had a hip replacement, you may need a DePuy hip replacement lawyer. On August 26, 2010, DePuy Orthopaedics, Inc. officially recalled two defective hip implant systems, the ASR Hip Resurfacing System and the ASR XL Acetabular System. The recall was ordered by the U. S. Food and g Administration (FDA) after receiving a high volume ofplaints from patients that had received one of these defective DePuy hip implants. The New York Times recently called the DePuy hip implant recall The most widespread medical implant failure in decades. After the recall, thousands of the estimated 93,000 all-metal hip replacement patients contacted a DePuy hip lawyer to find out if they may have a claim against the hip implant manufacturer.

DePuy is a subsidiary of Johnson amp Johnson. The DePuy ASR XL Acetabular Hip System and DePuy ASR Hip Resurfacing System have a 12 to 13 percent chance of failing within five years based on data from the National Joint Registry of England and Wales. In some cases, the DePuy ASR hip replacements failed after just a few years. Hip replacements are typically expected to last around fifteen years. A DePuy hip lawyer can help you determine whether or not your hip replacement system is at risk. The ASR systems were recalled due to a flaw in the design which can cause excessive friction between the metal parts. As a result of this flaw, the DePuy hip replacement products can loosen, causing severe pain, tissue damage, and even degeneration of the hip bones. The design flaw can be responsible for friction between the metal hip replacement parts which may then introduce excess cobalt and chromium ions into the patients blood stream.

The risk ofplications with the defective hip implants is highest for those patients with small stature, such as women, and for patients with weak bones. Contact a DePuy hip lawyer if your replacement is causing you pain or if it has been replaced sooner than expected. The recalled DePuy hip replacement systems can cause: Pseudotumors 8211 benign tumors made up of pus and scar tissue in response to the foreign object implanted in the body. Osteolysis thinning and weakened bones Increased levels of cobalt or chromium in the blood 8211 metal toxicity Loosening or dislocation of the hip implant Hip bone fracture or splintering Inflamed joint which canplicate revision surgery If a DePuy hip replacement patient develops the symptoms above it may be determined that the only treatment available to the patient is revision surgery (where the surfaces of the implants are surgically repaired) or replacement surgery (when the hipponents are removed and replaced by new devices). Unfortunately, revision or replacement surgery is usually riskier and moreplex than first time hip replacement surgery. Contacting a DePuy hip lawyer will help you to obtainpensation from DePuy for your additional medical costs, lost wages and suffering.

The DePuy metal-on-metal implants were faulty and in some cases the recalled implants have failed after just a few short years. The DePuy Pinnacle Hip Replacement System The Pinnacle hip replacement system was approved by the FDA in 2000 and is the predecessor to the recalled ASR and ASR XL systems. The two hip replacements systems, the Pinnacle and the ASR, are both metal-on-metal implants and are of similar design. While the Pinnacle has not yet been recalled, it is possible that a recall could be issued in the future. Patients that have received a Pinnacle device are also at risk for severe pain, loosening of the implant and metal toxicity. Because the Pinnacle is another all metal implant, many patients fitted with this system have had to endure painful revision surgery. The FDA has been evaluating this system as well as all other metal-on-metal hip replacement devices. Up until the DePuy recall, metal-on-metal hip implants were used in almost one-third of the approx.

250,000 hip replacements done each year in the US. It is important to be aware of symptoms of metal toxicity (metallosis) if you have received a metal-on-metal hip replacement. Effects of metallosis are not limited to the hip region only so it is important that you note any changes to your general health and speak with your medical professional if you have symptoms or changes in: Heart (pain or shortness of breath) Nerves (numbness or weakness) Changes in vision or hearing Thyroid (fatigue, weight gain) Kidney (frequent urination or other changes) Patients who have received a metal hip implant, especially the recalled DePuy systems or the metal-on-metal DePuy Pinnacle system, are encouraged to discuss the possibility of a lawsuit with a DePuy hip lawyer before it is too late to make a claim. Contacting a DePuy Hip Lawyer Because of the FDA ordered DePuy hip replacement recall, many patients are finding themselves wondering whether or not they may have a claim. A DePuy hip lawyer can help you evaluate your particular situation and help you determine whether or not you should file a lawsuit.

At D. Miller amp Associates, PLLC, a nationwide law firm dedicated to helping our clients receive justice, our experienced DePuy hip lawyer might claim that DePuy knew that there was a flaw in the design of the replacement. The DePuy hip lawyer will show how DePuy did not correct the flaw after they became aware of the problem. A DePuy hip lawyer is also likely to claim that DePuy failed to notify doctors or their patients in a timely manner that there is such a high risk of potential problems with their hip device. If you or someone you know has had a DePuy ASR, ASR XL, Pinnacle or other metal-on-metal hip device installed, please fill out the contact form on this page or call us at 1(866) 483-2649 for a free no-obligation evaluation of your case. The consultation is free and it is important to speak with a DePuy hip lawyer soon as the law does limit the time to file a DePuy hip replacement DePuy Lawsuit News Johnson amp Johnson Will Offer 2.5 Billion Hip Implant Settlement According to attorneys on the case, Johnson amp Johnson has agreed tooffer a settlement of nearly 2.5 billion to resolve pending lawsuits about its faulty metal-on-metal hip implants.

The settlement will require approval by the court, but it is expected to be announced in a the U. S. District Court of the Northern District of Ohio, the site of the multidistrict litigation, today according to court documents. The specifics of the plan are to vary on the amount of time the patient had the implant, with some patients receiving more and others receiving smaller amounts. The typical patient will receive around 250,000 under the plan, according to sources. The plan should cover approximately 8,000 patients who were forced to have the hip implant removed and replaced with another product. The DePuy ASR implant is one of the faultiest medical devices sold in recent years, with about 40 percent of implants failing within 5 years, nearly a third of the time they should last a patient. The ASR implant is not the only hip implant currently involved in litigation. Other hip implants manufactured by Stryker, Inc. and Zimmer Holdings, Inc. are also currently involved in litigation for similar failure problems.

This settlement offer is great news forour clients and others who have been injured by the ASR hip implant. These monies will go a long way in helping patients get back to a normal life, says Darren Miller, founding attorney of D. Miller amp Associates, PLLC. Click to read press release Press release 8211 Feary 8, 2013 According to internal documents, Johnson amp Johnson executives knew of a critical design flaw in the Articular Surface Replacement (ASR) hip implant years before it was recalled in 2010. The documents were disclosed during a trial related to the devices high failure rate during the plaintiffs lawyers opening argument. The ASR implant, manufactured by Johnson amp Johnsons DePuy Orthopaedics division, came on the market in the United States in 2005.

Concerns about the device started shortly after, when surgeons started noticing that the implants were failing early. Despite theplaints, DePuy continued to push the sale of the unit. In 2007, the device failed an internal testparing its performance to that of other hip implants. The ASRs flaw was in the design of the cupponent. The metal cup and ballb together and corrode, causing metal shards to be released into the surrounding blood and tissue. This can often lead to dangerous, even fatal, side effects. Even with this data, the device was not recalled until 2010. It is estimated that about 40 of patients who received the ASR implant will have the device fail within five years, eight times the failure rate of most hip implants.

This failure rate is even higher than was suspected at the time the device was recalled. ASR implants were used on 93,000 patients worldwide with about 28,000 done in the United States. Around 10,000 lawsuits have already been filed against Johnson amp Johnson for their defective hip implants. Jury awards 8.3 million in first JampJs DePuy hip trial March 8, 2013 A Los Angeles jury has awarded 8.3 million inpensatory damages in the first lawsuit against Johnson amp Johnson for their DePuy ASR XL hip implant. The jury stated that the metal-on-metal implant was defectively designed and JampJ was negligent. The jury also decided that DePuy properly warned of the risks and therefore did not owe punitive damages.

The plaintiff said that his ASR hip caused him to have additional revision surgeries as well as suffer from metal poisoning. His attorneys argued that DePuy failed to test the device before selling it in the U. S. in 2005 and downplayed theplaints of failures. The ASR hip was approved by the 510(k) clearance, which allowed the device toe to market without human testing due to its similarity to other hip implants. Because of this, the FDA issued new guidance for metal-on-metal hip implants which would make all metal hip implants ineligible for 510(k) clearance. JampJ recalled 93,000 DePuy ASR hip implants in August 2010 when 12 percent of the devices failed within five years. Current estimates now put the early failure rate at more than 40 percent, eight times the failure rate of most hip implants.

This lawsuit marks the first of more than 10,700 lawsuits filed against JampJ for their ASR hip. The verdict of this first trial proves that these injuries are substantial and the value for these lawsuits will be substantial. These lawsuits are expected to cost JampJ billions of dollars to resolve. D. Miller amp Associates, PLLC, who represent clients affected by defective hip implants, is encouraged by this verdict and hope it will be a sign of what can be expected with future ASR lawsuits. By contacting an attorney at D. Miller amp Associates, you will receive a free consultation to see if you can receivepensation for all of the medical costs and pain and suffering you have experienced from JampJs defective devices.

Press Release: Designer of DePuys recalled ASR hip implant tells jurors that he wouldnt implant the device today Houston, TX April 9, 2013 Orthopedic surgeon, Dr. Thomas Schmalzried, was the first defense witness to testify in the second lawsuit brought against Johnson amp Johnson subsidiary, DePuy Orthopaedics, Inc. for their recalled ASR hip implant. In the second of more than 10,000 lawsuits, the plaintiff alleges that the ASR hip implant was defective and caused severe injuries that required a revision surgery. Schmalzried testified on behalf of DePuy and stated that the devices were properly designed and developed but that he wouldnt rmend the implant today were it still on the market. Schmalzried also testified during the first DePuy ASR trial which resulted in an 8.3 million award for the plaintiff. During that trial, he testified that he had no knowledge of thepany department that collects and monitors allplaints for the metal implants and added that he no longer implants metal-on-metal devices. There has been some speculation as to whether Schmalzried has helped or hurt DePuys case with his surprising testimonies. DePuy has marketed the device as safe, however, it is estimated that about 40 of patients who received the ASR implant will have the device fail within five years, eight times the failure rate of most hip implants. This failure rate is even higher than was suspected at the time the device was recalled. Evidence has emerged during these trials that suggest that the device was defectively designed and that Johnson amp Johnson failed to properly warn about its risks.

D. Miller amp Associates, PLLC continues to accept new clients for defective hip implants. In many cases, those affected by these implants need painful revision surgery and even then, they may still experience pain and trouble walking. By contacting an attorney at D. Miller amp Associates, you will receive a free consultation to see if you can receivepensation for all of the medical costs and pain and suffering you have experienced from Johnson amp Johnsons defective devices. About D. Miller amp Associates, PLLC: Founded in 2002 by attorney Darren Miller, D. Miller amp Associates, PLLC is a premiere national law firm with practice areas in personal injury, asbestos and mesothelioma, defective gs and devices, business and criminal law. Based in Houston, Texas, the attorneys at D. Miller amp Associates, PLLC, have successfully earned their clientspensation through aggressive litigation against even the most powerful of defendants. For a free legal consultation, contact the firm at 1-855-PRO-LAWYERS or at marketingdmillerlaw. For more information, visit our website at dmillerlaw. For further information about our areas of service, please see our practice areas overview.

At Miller amp Law, P. C. we pride ourselves on giving answers - not theories. The hallmark of our firm is the broad scope of our practice, coupled with our reliance on a small group of highly-qualified professionals. We take a team approach to representation, drawing on the unique backgrounds of each of our nine skilled attorneys, whose diverse areas of expertise epass the business, accounting, and science fields. Our team includes trial lawyers, appellate attorneys, trained mediators, arbitrators, and hearing officers. In recognition of our work, national directory of attorneys Martindale-Hubbell has awarded us its prestigious AV-Preeminent rating. indicating the highest levels of professionalism and ethical standards.

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Tenaga Dalam Ilahi

Tenaga Dalam IlahiTenaga Dalam Ilahi Product Description DSI (Daya Sejati Insani) or initiation level Tenaga Dalam Ilahi known as TENDAI or Cosmic Inner Energy is not a martial arts discipline nor is it an internal energy training system that will enable you to walk on fire, eat glass, be bullet proof or shatter rocks amp bricks with your bare hands. TENDAI is a closely guarded secret, which has existed for several hundred years primarily originating from the Malay islands archipelago (Malaysia, Indonesia). 4 Inner Power Activations in one Package TENDAI is not a branch of any other inner power discipline, yet it is the most primary and fundamental basis upon which all other inner power schools have been developed. This is not intended to sound boastful or to act high and mighty as all power resides in GOD. We are not the only inner power system or only authority on such subjects. This is an invitation to share in our experience with Celestial Power as well as to help you understand your own experiences should any paranormal abilities manifest in you after initiation into TENDAI. In the event such things happen to you, it is because the creator (the source of all energy) wills it to be so. Ilmu Tenaga Dalam (Inner Power) Tenaga Dalam (Inner Power) can be raised by breathing practice, either by holding the breath inside the abdomen, chest or below the navelbined with concentration at a certain point. This kind of inner power can accumulate into a supernatural power that is filtered from Daya Hayat (life power)/ Daya Prana (Prana power)/ Maiks (maic power) that exist naturally and within us. However, if these powers are not routinely used or practiced regularly, they will disappear automatically over time. This is the basis of the Tridaya tenaga dalam method. Tenaga Dalam Ilahi (Celestial Prana) has a specifically different method from other prana or energy.

This celestial prana sources at our faith to God the Almightybined with full concentration. This prana will function forever and will automatically recharge itself after being used. The initiation process can be done directly or long distance. Celestial Prana consists of Divine Prana, Mental Prana and Physical Prana, thebination of the three will prevent the practitioner from being exhausted after practicing it. Most other Pranas have only one aspect that is the physical prana causing the practitioner to feel terrible fatigue after practice. Celestial Pranabines the three Pranas to automatically recharge itself after being used. In addition, the breathing techniques given in this manual will dramatically fasten the process.

The benefits after the 21-day initiation process may include: To have self protection against any physical or metaphysical attack To have the protection against injury from sharp tools (being attacked by an enemy) To cure physical or metaphysical diseases (Healing ability) To cure impotency To increase charisma and attraction To improve career and business To have the ability tomunicate and control khodam (occult guide) if you want to To be able to push away enemies before they even touch you. (Empty Force) To borrow other peoples supernatural power To be able to lock other peoples power or attack To create protection for self, other people, housepany and wealth The real key to make heirloom (to fill keris, machete, knife, samurai, jewel, oil for attraction and water) There is no prohibition, side effect nor contradictive to other white esoteric knowledge. It will even unite with these teachings. All supernatural powersing from God will unite. Any other knowledgeing from things or other beings will disappear. And many other benefits that are unique to each individual. Celestial Prana (TENDAI)es from divine faith and a clean and pure heart. It will eventually lead you to haveplete faith in God the Almighty. This knowledge will function forever and will never vanish. It is non contradictive to other pranas.

Understand that your initiation into Tenaga Delam Ilahi will activate your inner power. However in addition to the TENDAI empowerment, you will also receive empowerments for all three levels of TRIDAYA (Tenaga Delam, Ilmu Batin, Vibrotic Power) to further advance your development and understanding of inner power cultivation methods. You get all 4 initiations and manuals for 125.00. Thats right, you get the Tenaga Delam Ilahi (TENDAI) empowerment, plus all three levels of Tridaya initiations for one low price. Activate Daya Sejati Insani (DSI) your cosmic inner power now. You can search the all you want, but you will not find a better deal anywhere

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