Erectilisers and anti-rejection drugs such as carbamazepina and azathioprine are often prescribed to people with erectile problems, but some studies have shown that the drugs can be harmful.
Now, a new study finds that there is also a link between the drugs and erectile impairment in people with cystic fibrosis.
The study, which appeared in the Archives of Sexual Behavior, involved 679 men with cystitis and other cystic degenerative diseases who received either carbamazapine or azathoprine for one year.
Researchers found that those taking both drugs had significantly higher rates of erectile failure than those who received the drug only for cystic cystic disease.
For example, men who received azathopa had a 3.5 times greater rate of erections than those receiving carbamazape.
“There’s an association between the drug, and also the underlying disease, and the risk of erectiles being impaired,” said lead author Dr. Andrew Kohn, a professor of epidemiology at Johns Hopkins University in Baltimore.
“The drug doesn’t seem to have any benefit or any risk.”
For more about cystic neovascular syndrome, see the Sept. 9 issue of The New England Journal of Medicine.
For more on erectile disorders, see a story on this week’s cover of the Sept.-Oct. issue of Men’s Health magazine.
For a comprehensive overview of the effects of antidepressants on erections, see “Can Cystic Fibrosis Treat Depression?”
“Anecdotally, we’ve seen some people with severe depression and anxiety have difficulty with erections and that’s been a concern,” Kohn said.
The findings suggest that antidepressants might be helpful in treating erectile dysfunction.
A few drugs can help people with other conditions, such as cancer and HIV.
“We’ve found that people with the cystic forms of cystic Fibromyalgia are a subset of people with depression and other conditions,” Kern told Reuters Health by phone from the U.K. “That’s a really good sign that we might be able to help people who are not normally at risk.”
Kohn and his colleagues used data from the CysticFibromyalgia.com website, which collects and reports data on health care utilization, to calculate a range of potential interactions between the two drugs.
The results showed that carbamazopine and azametamphen were associated with increased risk of failure.
This is because people taking carbamazopa had more of a history of erectional dysfunction than people taking azamatamphen.
For instance, those who took azamamphen had a 1.8 times greater risk of failing a baseline test, while those taking carbazapine had a 2.2 times greater.
The researchers suggest that people who have erectile difficulties should not use carbamazone.
“It’s important to recognize that there are no specific side effects of either drug, nor are there any known side effects that might be a result of this combination,” Kahn said.
“If you’re having erectile difficulty, this combination of drugs might help.”